• Combined RBE and OER optimization in proton therapy with FLUKA based on EF5-PET 

      Henjum, Helge; Dahle, Tordis Johnsen; Mairani, Andrea; Pilskog, Sara Margareta Cecilia; Stokkevåg, Camilla Hanquist; Boer, Camilla Grindeland; Redalen, Kathrine Røe; Minn, Heikki; Malinen, Eirik; Ytre-Hauge, Kristian Smeland (Peer reviewed; Journal article, 2023)
      Introduction Tumor hypoxia is associated with poor treatment outcome. Hypoxic regions are more radioresistant than well-oxygenated regions, as quantified by the oxygen enhancement ratio (OER). In optimization of proton ...
    • A comparison of methods for fully automatic segmentation of tumors and involved nodes in PET/CT of head and neck cancers 

      Grøndahl, Aurora Rosvoll; Knudtsen, Ingerid Skjei; Huynh, Bao Ngoc; Mulstad, Martine; Moe, Yngve Mardal; Knuth, Franziska; Tomic, Oliver; Indahl, Ulf Geir; Torheim, Turid Katrine Gjerstad; Dale, Einar; Malinen, Eirik; Futsæther, Cecilia Marie (Peer reviewed; Journal article, 2021)
      Target volume delineation is a vital but time-consuming and challenging part of radiotherapy, where the goal is to deliver sufficient dose to the target while reducing risks of side effects. For head and neck cancer (HNC) ...
    • Head and neck cancer treatment outcome prediction: a comparison between machine learning with conventional radiomics features and deep learning radiomics 

      Huynh, Bao Ngoc; Grøndahl, Aurora Rosvoll; Tomic, Oliver; Liland, Kristian Hovde; Knudtsen, Ingerid Søberg Skjei; Hoebers, Frank; van Elmpt, Wouter; Malinen, Eirik; Dale, Einar; Futsæther, Cecilia Marie (Peer reviewed; Journal article, 2023)
      Background: Radiomics can provide in-depth characterization of cancers for treatment outcome prediction. Conventional radiomics rely on extraction of image features within a pre-defined image region of interest (ROI) which ...
    • Positron emission tomography guided dose painting by numbers of lung cancer: Alanine dosimetry in an anthropomorphic phantom 

      Papoutsis, Iosif; Knudtsen, Ingerid Skjei; Sande, Erlend Peter Skaug; Rekstad, Bernt Louni; Öllers, Michel; van Elmpt, Wouter; Arnesen, Marius Røthe; Malinen, Eirik (Peer reviewed; Journal article, 2022)
      Background and purpose Dose painting by numbers (DPBN) require a high degree of dose modulation to fulfill the image-based voxel wise dose prescription. The aim of this study was to assess the dosimetric accuracy of ...
    • Re-irradiation for recurrent rectal cancer – a single-center experience 

      Al-Haidari, Ghazwan Ahmed Dhia Eldin; Skovlund, Eva; Undseth, Christine; Rekstad, Bernt Louni; Larsen, Steinar; Åsli, Linn Merete; Dueland, Svein; Malinen, Eirik; Guren, Marianne (Peer reviewed; Journal article, 2020)
      Background: There is no clear consensus on the use of re-irradiation (reRT) in the management of locally recurrent rectal cancer (LRRC). The aim of the present study was to investigate all reRT administered for rectal ...
    • Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer 

      Slørdahl, Kathinka; Klotz, Dagmar; Olsen, Jan Åge; Skovlund, Eva; Undseth, Christine; Abildgaard, Heidi L.; Brændengen, Morten; Nesbakken, Arild; Larsen, Stein Gunnar; Hanekamp, Bettina Andrea; Holmboe, Laila Kampen Dajani; Tvedt, Ragnhild; Sveen, Anita; Lothe, Ragnhild Adelheid; Malinen, Eirik; Kaasa, Stein; Guren, Marianne Grønlie (Journal article; Peer reviewed, 2021)